This how to Remove most of paltalk ads manually, I saw it on dep site
In Vista and Windows 7
1) Browse to Start -> All Programs -> Accessories
2) Right click "Notepad" and select "Run as administrator"
3) Click "Continue" on the UAC prompt
4) Click File -> Open
5) Browse to "C:\Windows\System32\Drivers\etc"
6) Change the file filter drop down box from "Text Documents (*.txt)" to "All Files (*.*)"
7) Select "hosts" and click "Open"
Add this
127.0.0.1 ads.addynamix.com
127.0.0.1 client.paltalk.com
127.0.0.1 http://www.ads.addynamix.com
127.0.0.1 ad.yieldmanager.com
127.0.0.1 advertising.paltalk.com
127.0.0.1 banners.addynamix.com
9)Make the needed changes and close Notepad. Save when prompted.
You can find the file in other OS as follows
Windows 95/98/Me c:\windows\hosts
Windows NT/2000/XP Pro c:\winnt\system32\drivers\etc\hosts
Windows XP Home c:\windows\system32\drivers\etc\hosts

The room ads are blocked but I still get the ads on the rooms list screen...